The price of one barrel of oil is equivalent to one gram of snake venom

     The researchers of Razi Vaccine and Serum Institute have succeeded in extracting a combination of snake and scorpion venom called “ICD” which stopped the growth of cancer cells by 20% and caused the natural death of these cells.

This substance has actually turned a malignant cancerous mass into a benign one. Dr. Abbas Zare Mirkabadi, the head of the Department of Poisonous Animals and Antidote Preparation of Razi Institute, announcing this news, tells Khorasan: Currently, these experiments are continuing on mice suffering from cancer, and the transformation of this drug into microcapsules will be done soon.

He adds: The antidotes produced by Iranian researchers are the first in the Middle East region in terms of quality, quantity and variety, and are able to compete with well-known western countries in this field. Dr. Zare says: Every year, 85,000 ampoules containing snake and scorpion antidote are prepared for domestic use and 7 to 10,000 ampoules for export. Each ampoule containing 10 cc of antidote is exported for $52, but its global price is $40. In other words, every 10 cc of snake antidote made by Iranian experts is worth about 70 liters of oil. In fact, from each gram of dry snake venom, about 1,500 vials of antidote are produced (each vial is equivalent to 10 cc).

With a simple calculation, we can come to the conclusion that each gram of dry snake venom is equivalent to 680 barrels of exported oil.

The head of the poisonous animals and antidote preparation department of the Vaccine and Serum Research Institute Razi says: The department of venomous animals started its activity 40 years ago, and after making monovalan and tetravalan antidotes, it has now succeeded in making polyvalan, which is able to neutralize the venom of 6 different types of dangerous poisonous snakes. In addition, anti-scorpion serum produced by Iranian experts is effective against 6 types of scorpion venom.
Dr. Abbas Zare Mirkabadi says: Every year, 85 thousand ampoules containing snake and scorpion antidote are produced and delivered to the Ministry of Health, and about 7 to 10 thousand ampoules are also exported to the countries of the region. Each ampoule contains 10 cc of snake antidote, which can be injected up to 20 ampoules depending on the severity of the symptoms.
Each ampoule containing antidote is exported for $25 to the countries of the region, including Jordan, and if there is a demand for scorpion antidote, there is the ability to export it.

Dr. Zare adds: The antidote for poisonous spiders has not been made in Iran yet, but the researchers of the center have presented a plan to investigate the distribution of spiders and so far they have been able to complete 60% of it. Based on this, 2 species of dangerous poisonous spiders have been observed, which are mostly scattered in Khorasan and Central Province.
The researches in this field have led to the knowledge of spider venom antidote production in Eshel Laboratory, which we are trying to mass produce in the coming years. Spider venom affects children more than adults. Therefore, it is necessary to make spider antidote quickly to reduce the length of the treatment period.
The head of the department of poisonous animals of Razi Institute, referring to the research conducted by Iranian experts on bee venom, says that we are studying the effect of different doses of bee venom on laboratory mice suffering from rheumatism.
According to him, so far 75 species of snakes and 23 species of scorpions have been identified in Iran, and it should be noted that the antidote of each poisonous animal is specific to that animal, meaning that the antidote of one species of snake cannot be used for another species.
Dr. Zare explains the different stages of producing antidote from snake venom and says: After being poisoned by a snake or scorpion, the poison dries up and turns into a powder.
This powder is mixed with a compound called “Yavar” and is injected subcutaneously to the horse with a small dose for several times (6 to 10 times). When the appropriate amount of antidote is made in the horse’s blood, blood sampling is done and then the horse’s blood plasma is separated. After purification and enzymatic digestion, the serum is precipitated. After the formulation is done and the amount of antivenom reaches the desired concentration, different tests and control tests are performed on it, and after all the tests are confirmed, the antivenom is packaged and handed over to the Ministry of Health.
According to the Head of Poisonous Animals Department of Razi Institute, since 10 years ago, Iranian researchers have started researches on different animal poisons and have been able to identify and purify the toxins in different scorpion venoms, their amino acid sequence and 3D structure in Identify scorpion poisons and find out how they affect animals by studying the effects of these poisons on animals.

In addition to this, since last year, we have started extensive research on the possibility of treating some incurable diseases such as cancer by protein peptides found in snake and scorpion venoms, and with a unique achievement, we have succeeded in making a combination of animal venoms called “ICD 58”, which is in the stages of development. A laboratory has caused the destruction of cancer cells and inhibited their growth by 02%, as well as the natural death of these cells. Dr. Zare says in explaining the future plans: We are going to create animal models of MS and investigate the effect of venom and scorpion on this disease.

And he notes: No antidote has been made for people who are sensitive to bee stings in the country, but after being stung by a bee, they can use anti-allergic drugs such as antihistamines. Of course, the use of these drugs does not rule out visiting a doctor.
Dr. Meer Jalali, the professor of pharmacology and toxicology department of Ahvaz Jundishapur University also announced in a conversation with Khorasan: during researches on the poison of the scorpion, Jundishapur Ahvaz University experts succeeded in isolating the biologically active part of scorpion venom called OD1 and 2 types of specific toxins with the names ODK1 and ODK2 became from this scorpion. In the research conducted by Iranian researchers, it was found that ODK2 is a specific poison effective on the potassium channel “KV 1.03”. This channel has a proven role in the occurrence of MS disease (MS is an autoimmune disease) and according to the findings of Iranian researchers that ODK2 has a controlling role on this channel, therefore it can effectively control MS disease and this issue It can be the basis of tests on MS disease and the effect of this poison on its improvement. This toxin is actually the first specific toxin related to channel 3 of potassium voltage. He added: So far, 3 articles have been published about Jarareh Scorpion in prestigious international magazines.

 

Only 20% of the snakes in the world are poisonous, of which 75% are capable of killing humans with their venom.

Deutsche Welle Germany: Humans are usually afraid of snakes, and in many cultures unbelievable legends are told about snakes, but the medical use and obtaining medicine from snake venom in an industrial way is a new story in recent years.
Although there are many types of snakes in the world, only 20% of snakes are poisonous, which are usually identified by signs such as a thin tail and the presence of two hollow sharp teeth with a hole in the beginning, and the rest of the snakes are non-poisonous.
Also, out of these 20% of poisonous snakes, only 75% of them are able to kill humans with their venom.
A pharmaceutical company in Germany is engaged in a special farm for the keeping and breeding of poisonous and rattlesnakes. “Rolf Kreutz” is in charge of the snake farm where more than 200 poisonous snakes are kept, and this farm belongs to the “Nordmark” pharmaceutical company and is near Hamburg. Is.
Most of the poisonous snakes are rattlesnakes from Malaysia. The length of this type of snake reaches 50 to 70 centimeters, and their skin has black and brown colors, and the main food of snakes is mice.
A live mouse is food for a snake for 21 days and the snakes are kept separately in large plastic boxes. During the days, the snakes hang out in their box with a unique calmness, but getting close to these snakes can have dire consequences.
Kravitz said about the effects of snake venom on the human body: “At the beginning of entering the human body, this poison destroys the tissues and destroys the arteries, which in some cases leads to the loss or paralysis of the bitten organ.” Studying the healing effects of venoms in this pharmaceutical company, experts believe that snake venoms also have healing effects.
Specifically, it can be used as primary drugs in brain and heart attacks. In such attacks, which are faced with blockage of arteries and blood clots, blood does not reach the brain and part of the cells are destroyed forever.
In such cases, a poisonous substance obtained from snakes called “Ancrod” should be used, as this substance causes rapid blood thinning.
“Manfred Kurforst”, responsible for the production of biological drugs, said about the effect of this substance: “Blood coagulation can be removed in this way, and after a brain attack, the concentration of blood increases, and by using this substance, it can be diluted again, and the diluted blood is able to wash the parts where it was impossible to get blood before.” “
If this effective substance is used up to six hours after a brain attack, we can hope to prevent possible brain damage.
Currently, the results of two studies are available. One in America, which has been successful, and the other in Europe, which statistically cannot show the effect of this substance everywhere.
This effective substance in Europe has not yet received an official license. The Nordmark pharmaceutical company in Germany is of the opinion that patients with very dangerous diseases have participated in their tests and these people have had a negative impact on the statistical results.
Currently, this pharmaceutical company with its partner in America is trying to arrange a trial with 1,700 patients.